Institute of Macromolecular Chemistry, AS CR

http://www.imc.cas.cz/cz/umch/

University of Oslo

Oslo University Hospital

Charles University in Prague

This project is devoted to develop innovative nanoparticle toolbox, consisting of a new generation self-organized polymer-based materials that could be used for biomedical applications in cancer, tuberculosis and inflammation treatment. The tools consist of biodegradable polymeric nanoparticles; their surface will be covered by a polymer that carries groups targeting specific receptors on theranostic target and groups allowing complexation of the polymer to the nanoparticle. The new systems will be tested for their anti-cancer activity, anti-bacterial and anti-inflammatory activity using in vitro cell cultures and in vivo models of the diseases.

1 322 981 EUR