Tissue engineering of genetically competent corneal/conjunctival cells for subsequent grafting in human medicine
Published
Updated 23-12-2014
- region changed
| Region | National coverage |
|---|---|
| Title of the Programme | Czech-Norwegian Research Programme |
| Title of the Project | Tissue engineering of genetically competent corneal/conjunctival cells for subsequent grafting in human medicine |
| Number of the Project | 7F14156 |
| Project Promoter |
Charles University in Prague |
| Name of Norwegian Partner(s) |
Oslo University Hospital, NILU – Norwegian Institute of Air Reserarch |
| Name of Local Partner(s) |
University Hospital Kralovske Vinohrady |
| Objective of the Project |
The overall objective of this proposal is to help to alleviate the dual problem facing transplantation medicine, of shortage of donor tissues, and the relatively short storage time. We will develop novel, improved protocols for preparation of corneal (endothelial and epithelial) and conjunctival (epithelial and goblet) cells for potential grafting in human medicine. Throughout, we will monitor the viability of cells and tissues using established tests for DNA integrity and DNA repair capability. Vitrification will be introduced as a potential method for indefinite storage of cells/tissue for grafting. |
| Approved grant |
872 491 EUR |
| Project Duration | Start date: 7th August 2014, End date: 30th April 2017 |