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Efficient Low-energy Electron Cancer Therapy with Terbium-161

Department 58 – International Relations
Department 58 – International Relations

Published

Project
Region Prague
Title of the ProgrammeResearch
Title of the ProjectEfficient Low-energy Electron Cancer Therapy with Terbium-161
Project Website

https://electtra.cz/

Number of the ProjectTO01000074
Project Promoter

České vysoké učení technické v Praze

Project Partner from Donor State

Oslo University Hospital
Institute for energy technology

 

Czech Partner

Centrum výzkumu Řež s.r.o.
Ústav makromolekulární chemie AV ČR, v. v. i.

 

Status

Estimated project duration: 1 / 2021 - 4 / 2024

Total Eligible Costs

1 487 629 EUR

Grant

1 327 179 EUR

Project description:

The main aim of the project is the R&D of novel radiopharmaceuticals based on terbium-161 and novel vectors for targeted therapy of tumors.

The advantage of Tb-161 is in the emission of large numbers of low energy electrons followed by gamma radiation allowing tomographic imaging and therapy follow-up. This will allow targeting of single cancer cells, micrometastases and whole tumors, particularly in early stages of diseases to increase the treatment efficiency.

Project results include not only the Tb-161 production in relevant quantity, but also novel targeting molecules (see project results). Collaboration between the Czech and Norway highly experienced partners in the research, development and commercialization of the results has all prerequisites to reach the proposed results.