Efficient Low-energy Electron Cancer Therapy with Terbium-161
Published
Region | Prague |
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Title of the Programme | Research |
Title of the Project | Efficient Low-energy Electron Cancer Therapy with Terbium-161 |
Project Website | |
Number of the Project | TO01000074 |
Project Promoter | České vysoké učení technické v Praze |
Project Partner from Donor State | Oslo University Hospital
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Czech Partner | Centrum výzkumu Řež s.r.o.
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Status | Estimated project duration: 1 / 2021 - 4 / 2024 |
Total Eligible Costs | 1 487 629 EUR |
Grant | 1 327 179 EUR |
Project description:
The main aim of the project is the R&D of novel radiopharmaceuticals based on terbium-161 and novel vectors for targeted therapy of tumors.
The advantage of Tb-161 is in the emission of large numbers of low energy electrons followed by gamma radiation allowing tomographic imaging and therapy follow-up. This will allow targeting of single cancer cells, micrometastases and whole tumors, particularly in early stages of diseases to increase the treatment efficiency.
Project results include not only the Tb-161 production in relevant quantity, but also novel targeting molecules (see project results). Collaboration between the Czech and Norway highly experienced partners in the research, development and commercialization of the results has all prerequisites to reach the proposed results.