Low-temperature 3D Printing of Bio-Functionalized Ceramic Bone Implants with Adjustable Mechanical Properties
Published
Region | South Moravian Region |
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Title of the Programme | Research |
Title of the Project | Low-temperature 3D Printing of Bio-Functionalized Ceramic Bone Implants with Adjustable Mechanical Properties |
Project Website | |
Number of the Project | TO01000309 |
Project Promoter | Vysoké učení technické v Brně |
Project Partner from Donor State | Genis hf.
|
Czech Partner | Univerzita Karlova |
Status | Estimated project duration: 1/2021 – 12/2023 |
Total Eligible Costs | 1 433 472 EUR |
Grant | 1 375 622 EUR |
Project description:
The aim is to establish close interdisciplinary cooperation between Czech and Icelandic partners for the development of biofunctional polymer-ceramic ink for low-temperature 3D printing of patient-specific bone implants.
The goal is to improve the mechanical, degradable, healing and antibacterial properties of printed implants by modifying ceramic cement with binders based on biodegradable synthetic polymers and bioactive polysaccharides and proteins.
The effiency will be verified by implantation of 3D printed parietal bone into rat skull defect. Results: 2 utility models of cement suitable for 3D printing of implants with adjustable mechanical properties (D1) and increased biological activity (D2) and 1 functional sample of the 3D printed parietal bone with increased bioactivity (D3).